Most prior authorization denials are decided well before the request is sent. These six cases show where they start and what stops them.
Key Takeaways
- Every case in this series turned on one question: is this request ready to submit?
- Three of the six were documentation problems. The other three were plan problems: a formulary, a federal exclusion, and a network.
- Faster submission would not have fixed any of them. A trained reviewer reading the chart and the plan first would.
Every new prior authorization specialist at DataMatrix Medical works through cases like these before touching a live queue. Each one comes from a real request our team handled. Each one is built around a pattern we see every week.
The patterns matter because denials come from specific places. In an internal review of 1,192 denials across all specialties, every one traced back to clinical judgment: 59% for clinical criteria not met, 26% for not medically necessary, and 15% for both. None of those are problems a faster portal fixes.
Source: DataMatrix Medical internal data, based on denials across all medical specialties.
Here are the six cases, what put each request at risk, and what our team did.
The six cases
Case 1 | Spine / Orthopedics
The lumbar MRI missing six weeks of proof
Plan: Healthfirst, reviewed by eviCore
What put it at risk: Spine MRI with no documented six-week course of conservative treatment.
A spine MRI request headed to eviCore with no documented conservative care. We paused, requested the treatment notes, and built a submission that answers the reviewer’s first question.
Case 2 | Neurology / Botox
The Botox request that said “neck pain”
Plan: A Blue Cross Blue Shield plan
What put it at risk: Botox request with short, nonspecific chart notes and no recent exam.
No specific diagnosis, no treatment history, and a seven-month-old note. We flagged all three gaps before the request reached the plan.
Case 3 | Ophthalmology / Specialty Rx
The Xiidra request that skipped a step
Plan: Aetna Medicare HMO
What put it at risk: A branded medication was requested when a preferred formulary alternative had not been tried.
A branded dry eye drop was headed to an Aetna Medicare HMO with no formulary check. We found the step-therapy requirement first and gave the prescriber two clear paths forward.
Case 4 | Pain Management
The fourth facet injection with no endpoint
Plan: Fidelis Care
What put it at risk: Fourth lumbar facet injection with no documented plan for what comes next.
Three injections in ten months, a good response, and no plan for what came next. We caught the missing ablation plan before the reviewer did.
Case 5 | Primary Care / Pharmacy
The prior auth we recommended not submitting
Plan: Humana Medicare Advantage with Part D
What put it at risk: Erectile dysfunction medication submitted under Medicare Part D.
An erectile dysfunction drug was headed to a Medicare Part D plan, where federal law excludes it. We stopped the request and told the practice right away.
Case 6 | Pain Management
The nerve block sent to the wrong network
Plan: Healthfirst HMO
What put it at risk: Prior authorization submitted with a rendering provider outside the patient’s network.
An HMO member was referred to an out-of-network specialist. We caught the network problem before submission and escalated it with the practice.
What the six cases have in common
Different specialties, different plans, different triggers. The same three habits prevented the denial in every one.
- Read the chart before the portal. The specialist confirms the documentation answers the payer’s questions before entering anything.
- Check the plan before the clinicals. Formulary placement, plan exclusions, and network status can sink a clinically perfect request.
- Pause when it’s thin. Holding a request for a day to get the right notes is better than a denial that takes weeks to appeal.
The payers in these cases
- eviCore by Evernorth: A medical benefits management company owned by Cigna through its Evernorth health services business. It reviews prior authorizations for specialized services, such as advanced imaging, on behalf of many health plans.
- Carelon Medical Benefits Management: Elevance Health’s specialty utilization management business, which handles prior authorization review in specialized clinical areas.
- Evolent: A specialty care management company that health plans hire to manage areas such as oncology, cardiology, musculoskeletal care, and advanced imaging.
- Healthfirst: A not-for-profit New York health insurer founded by downstate hospital systems, offering Medicaid, Medicare Advantage, and commercial plans.
- Fidelis Care: A New York health plan offering Medicaid, Medicare Advantage, marketplace, and other coverage. It has been Centene’s New York plan since 2018.
- Wellcare and Ambetter: Centene brands. Wellcare offers Medicare Advantage and Part D plans; Ambetter offers marketplace plans.
- Premera Blue Cross: A Blue Cross Blue Shield plan serving Washington and Alaska.
- Aetna, Humana, UnitedHealthcare, and BCBS plans: National and regional insurers whose commercial, Medicare Advantage, and Part D products each carry their own prior authorization rules.
Sources: The Cigna Group Form 10-K (eviCore); Elevance Health Form 10-K (Carelon); Evolent; Healthfirst, About Us; Centene, Fidelis Care announcement
A question for your team
If you pulled ten of last month’s denials, how many were decided before you sent the request?
Want a prior authorization team that reads the chart and the plan before every submission? Talk with DataMatrix Medical.
These cases are drawn from real prior authorization requests our team handled. We removed identifying details to protect patient privacy. Payer policies change and vary by plan, so the same steps will not produce the same result in every case. This article is educational and is not legal, billing, or clinical advice.

Nathaniel Smathers is the VP of Client Education and Marketing. He is also a long time contributor of the DataMatrix Medical blog and has a background in healthcare content creation for over a decade. Nathaniel is passionate about exploring the intersections of healthcare, data analysis, and digital innovation.
